WebSTING1 gene stimulator of interferon response cGAMP interactor 1 Normal Function The STING1 gene provides instructions for making a protein that is involved in immune system function. STING helps produce beta-interferon, a member of a class of proteins called cytokines that promote inflammation. WebApr 4, 2024 · Stimulator of interferon genes (STING) activation exacerbates experimental colitis in mice. Redox homeostasis maintained by GPX4 facilitates STING activation. Enhancing Immune Response and Heterosubtypic Protection Ability of Inactivated H7N9 Vaccine by Using STING Agonist as a Mucosal Adjuvant.

72512 - Gene ResultSting1 stimulator of interferon response …

WebApr 13, 2024 · Administration of DMX, the activator of stimulator of interferon genes (STING), was performed to investigate the effects of the STING-related pathway on APAP … WebDec 14, 2024 · In the classic Cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) synthase (cGAS)-stimulator of interferon genes (STING) pathway, downstream signals can control the production of type I interferon and nuclear factor kappa-light-chain-enhancer of activated B cells to promote the activation of pro-inflammatory molecules, … can ayou see chixulub from space

The cGAS–STING pathway: more than fighting against viruses and …

Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a protein that in humans is encoded by the STING1 gene. STING plays an important role in innate immunity. STING induces type I interferon production when cells are infected with intracellular … See more Amino acids 1–379 of human STING include the 4 transmembrane regions (TMs) and a C-terminal domain. The C-terminal domain (CTD: amino acids 138–379) contains the dimerization domain (DD) and the See more The subcellular localization of STING has been elucidated as an endoplasmic reticulum protein. Also, it is likely that STING associates in close proximity with mitochondria associated ER membrane (MAM)-the interface between the mitochondrion and … See more STING mediates type I interferon immune response by functioning as both a direct DNA sensor and a signaling adaptor protein. … See more • Wang Y, Tong X, Omoregie ES, Liu W, Meng S, Ye X (Oct 2012). "Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible gene I-like receptor-mediated immune signaling in a ubiquitination-dependent manner". The Journal of Biological … See more STING is expressed in hematopoietic cells in peripheral lymphoid tissues, including T lymphocytes, NK cells, myeloid cells and monocytes. It has also been shown that STING is highly expressed in lung, ovary, heart, smooth muscle, retina, bone marrow and vagina. See more STING mediates the type I interferon production in response to intracellular DNA and a variety of intracellular pathogens, including viruses, intracellular bacteria See more • STING agonist See more WebApr 4, 2024 · Sting1 stimulator of interferon response cGAMP interactor 1 [ Mus musculus (house mouse) ] Gene ID: 72512, updated on 4-Apr-2024 Download Datasets Summary Official Symbol Sting1 provided by MGI Official Full Name stimulator of interferon response cGAMP interactor 1 provided by MGI Primary source MGI:MGI:1919762 WebOxidative stress impairs mitochondria, releasing mitochondrial DNA into the cytoplasm and inducing inflammation through the intracytoplasmic DNA sensor STING (stimulator of interferon genes). However, the role of innate immunity in … can a youtube channel block you