WebApr 1, 2024 · Download Citation On Apr 1, 2024, Andreas Begitt and others published A family-wide assessment of latent STAT transcription factor interactions reveals divergent dimer repertoires Find, read ... WebThe 35 probes regulated by both wild-type STAT1 and Y701F-STAT1 represent 30 distinct genes. More than half of these (17 of 30) function in immune responses (Table 1). The …
Therapeutic targeting miR130b counteracts diffuse large B-cell
WebJul 1, 2013 · We further discovered that, although the Tyr (701) phosphorylation site is inducible (within 15 min of IFN-γ exposure), the Ser (727) site within STAT1 is constitutively phosphorylated. Thus, we generated single-mutant STAT1 Y701F and double-mutant STAT1 Y701F/S727A adenoviruses. WebY701F GenBank ID M97935 Entrez Gene STAT1 ( a.k.a. CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91) Tag / Fusion Protein Flag (C terminal on insert) Cloning Information Cloning method Restriction Enzyme 5′ cloning site NotI (not destroyed) 3′ cloning site ApaI (not destroyed) 5′ sequencing primer T7 3′ sequencing primer SP6 dvla office london
Phosphorylation-deficient Stat1 inhibits retinoic acid–induced ...
WebThe complexity of STAT1 signaling in innate immunity is further highlighted by the existence of a non-canonical STAT1 pathway. STAT1 Y701F mutant proteins that cannot be activated by JAKs in the canonical manner … WebLentiviral expression of Y701F-STAT1. Depositor. George Stark. Article. Cheon et al Proc Natl Acad Sci U S A. 2009 Jun 9;106. Insert. STAT1 (STAT1 Human) Use. Lentiviral Tags. FLAG . Expression. Mutation. Y701F. Promoter. CMV. Availability. Academic Institutions and … WebSTAT1 protein levels were similar in monocytes recovered before and after initiation of ivacaftor . However, consistent with the decrease in ISG expression, IFN-γ-induced STAT1 … dvla office worcester