http://pedorthicsolutions.com/about.php WebThe steps above are carried out by a large enzyme complex called the pyruvate dehydrogenase complex, which consists of three interconnected enzymes and includes over 60 subunits. At a couple of stages, the reaction intermediates actually form covalent bonds to the enzyme complex—or, more specifically, to its cofactors.
Pyruvate oxidation Cellular respiration (article) Khan Academy
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