2024 K14-cre

K14-cre

Author: syei

August undefined, 2024

WebbK14-Cre小鼠与FloxP小鼠交配后，在Cre特异表达的组织或者器官或细胞中，两个FloxP位点间的外显子或元件将被删除，达到条件性敲除或过表达的目的。可用于皮肤等相关研究。

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Webb15 jan. 2009 · Re-epithelialization after skin wounding requires both migration and hyperproliferation of keratinocytes. Laminin-332 is deposited during migration over the provisional matrix. To investigate the function of the laminin-332 binding integrin α3β1 in wound re-epithelialization, we generated Itga3flox/flox; K14-Cre mice lacking the α3 … WebbTg (KRT14-cre/ERT2)1Ipc. Show the 4 phenotype image (s) involving this allele. Mutation details : This transgene expresses a tamoxifen-inducible form of cre recombinase in the epidermis, tongue, esophagus, stomach, and other epithelial tissues. ( J:65109 ) goku death battle fanon

表皮角蛋白的表达及表皮分化 - 皮肤病学 - 天山医学院

Webb在目前报道的角蛋白基因中，很多在表皮及其附属器有表达。角蛋白的表达随表皮向终末分化的过程而改变。 K1/K10以及K5/K14是在人表皮表达的4种主要角蛋白。 K5/K14是在表皮增生性基底细胞表达的蛋白对，而K1/K10是在基底层上分化性表皮细胞主要表达的角蛋白对。在基底层上还有K2e及K9的表达，但它们主要特异性地表达在掌跖部表皮。 K2e … WebbArticle Snippet: Mice expressing Cre recombinase under control of the human keratin 14 (K14) promoter ( Krt14-Cre ) [stock no. 004782, STOCK Tg( KRT14-Cre )1Amc/J] ( 35 ) and mice carrying loxP sites flanking exon 6 of Rptor (stock no. 013188, B6.Cg- Rptor tm1.1Dmsa /J) ( 37 ) were from The Jackson Laboratory. Webb1 nov. 2024 · 2.2.Deletion of mTOR in tooth epithelia caused dis-morphogenesis and cystogenesis in the EO. Next, we performed a thorough phenotypic analysis of the K14-Cre; mTOR loxp/loxp cKO mice. Mutant mice died shortly after birth, in agreement with a recent report (Ding et al., 2016).At the newborn stage (P0), teeth of mutants showed … goku custom head sculpt

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004782 - K14-Cre Strain Details - The Jackson Laboratory

Webb20 juli 1999 · With K14–Cre, transgenic embryos recombine genetically introduced loxP sequences efficiently and selectively in the genomes of keratinocytes that reside in embryonic day 14.5 skin, tongue, and esophagus. With K14–CreER tam, postnatal transgenic mice show no Cre activity until tamoxifen is administered. WebbKaspersky Security Center takes the complexity out of security administration and IT systems management. Buy as a part of Kaspersky Endpoint Security for Business … goku cutting offWebb3 sep. 2024 · Nude mice were used for transplantation with mouse MMTV-PyVT, K14-Cre;Brca1 f/+;p53 f/+ tumor cells, human breast cancer PDX cells or human breast cancer cell lines. hazleton children and youth

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K14-cre

Hair Follicle Stem Cells Are Specified and Function in Early Skin ...

Webb27 juni 2024 · Our previous study using K14-Cre;R26R mice demonstrated intense β-gal-positivity (an indicator for Cre activity) among the cells at the epithelium overlying the palatal process of the secondary and primary palates (Sarper et al., 2024). This was also evident in the contacting and fused epithelium in anterior palatogenesis. WebbInsertion. Mutation details : Expression of Cre recombinase in the basal layer of the epidermis, the outer root sheath of the hair follicle and the oral epithelium, driven by the human keratin 14 promoter/enhancer (KRT14). Promoter is active by embryonic day 14.5 (E14.5). ( J:56822 )

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Webb26 juni 2024 · Krt14 Cre;Isl1 fl/fl mice appeared normal and healthy, with the exception of incisor enamel defects, including altered enamel on the labial surface and ectopic enamel on the lingual surface, where enamel is not normally formed. Interestingly, molar teeth were not affected. Multiple signaling pathways, including Bmp, ... Webb15 dec. 2024 · K14 Cre (MGI: 1926500) and K14-H2BGFP (MGI:5286142) mice were provided by E. Fuchs. Ifngr1 KO mice (Jackson stock no. 003288) and Tek Cre mice …

Webb17 maj 2024 · We also generated the K14-Cre;tdTomato;Mettl3fl/fl mice, in which K14 + cells and their daughter cells were labeled with tdTomato fluorescence, and confirmed … Webb基づき、検討を行うこととした。具体的にはCre-loxP系を用い、重層扁平細胞の基底部に発現するKeratin 14 (K14)のプロモーター下流に部位特異的組み替え酵素Creを発現して表皮角化細胞特異的ノックアウトマウスを作成するために

Webb17 maj 2024 · Deletion of Mettl3 in epidermal progenitors leads to taste bud defects. As previously described, basal progenitors develop into taste cells (K8) and differentiated keratinocytes (K13) (Fig. (Fig.1a 1a) 15,16,40.To explore whether deletion of Mettl3 affected taste bud development, we crossed Mettl3 fl/fl mice 28 with K14-Cre … WebbThe hyperproliferative, inflammatory skin disease in K14-Cre-IKK2fl/fl mice was a direct consequence of the presence of macrophages in the skin, as targeted deletion of …

WebbThese K14-Cre transgenic mice are a Cre-lox tool useful for deletion of floxed sequences in the ectoderm and its derivatives (including the skin, dental epithelium, and oral …

WebbAlla våra läkare har minst 6 månaders erfarenhet från den fysiska primärvården. Hos Kry arbetar även flera specialister inom bland annat pediatrik, akutsjukvård och … goku countingWebbThree mouse lines expressing Cre recombinase under the control of the human K14 promoter induced specific deletion of loxP flanked target sequences in the epidermis, in tongue, and thymic epithelium of the offspring where … goku cycles tootingWebbLooking for online definition of K14 or what K14 stands for? K14 is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms The … goku death beamWebb005107 STOCK Tg(KRT14-cre/ERT)20Efu/J These transgenic mice have a tamoxifen inducible Cre-mediated recombination system driven by the human keratin 14 ( KRT14 … goku death battleWebbK14-Cre小鼠. 分类: Cre鼠发布时间: 2024-07-11 11:00. 应用：皮肤. 级别：SPF. 类型：TG/KI. 背景：C57BL/6. 该Cre小鼠与FloxP小鼠交配后，在Cre特异表达的组织或者器 … hazleton charitiesWebb19 juli 2024 · We also generated k14-cre; Sox2 fl/fl mice to explore the function of Sox2 during mouse incisor development. And this K14cre-driven recombination activates at around 11.75, which is much later than the Shh-cre and Pitx2-cre. And k14-cre; Sox2 fl/fl mice can survive and grow up with normal incisor morphogenesis (data not shown). goku death battle biohttp://www.labmodel.cn/mod_product-view-p_id-4619.html goku crypto gameplay.com