WebThe two thyroid hormones, thyroxine (3,5,3′,5′-tetraiodothyronine) and 3,5,3′-triiodothyronine, are formed by the addition of iodine to an amino acid (tyrosine) component of a glycoprotein called thyroglobulin. Thyroglobulin is stored within the gland in follicles as the main component of a substance called the thyroid colloid. This arrangement, which provides … WebReaccumulation of thyroglobulin only occurred if there was concomitant organification of at least some iodine. The subsequent phases of depletion and reaccumulation of thyroglobulin were mirrored by the morphology of the follicular lumina, the staining properties of the colloid and the serum T4 concentration.
Hormone - Hormones of the thyroid gland Britannica
WebThe oxidation of two iodide ions (2 I –) results in iodine (I 2), which passes through the follicle cell membrane into the colloid. In the colloid, peroxidase enzymes link the iodine to the tyrosine amino acids in thyroglobulin to produce two intermediaries: a tyrosine attached to one iodine and a tyrosine attached to two iodines. WebThyroid hormone synthesis includes the following steps: (1) iodide (I-) trapped by the thyroid follicular cells; (2) diffusion of iodide to the apex of the cells; (3) transport of iodide into … ipod touch authorize new mac
Diffusion of thyroglobulin in the follicular colloid. (Minireview)
WebThyroglobulin (Tg) is a large (660 kDa) glycoprotein, which is the site of synthesis of T 3 and T 4 in thyroid follicular cells. It also acts as a large storage reservoir of thyroid … WebThyroglobulin is stored within the gland in follicles as the main component of a substance called the thyroid colloid. This arrangement, which provides a reserve of thyroid … WebTHYROID FUNCTION. The functional units of the thyroid gland are multiple, variable-sized follicles, formed by a single layer of epithelial cells, filled with colloid (a proteinaceous material containing thyroglobulin, a glycoprotein necessary for the synthesis of T3 and T4). At high magnification the cell surface lining the follicle is rich in ... orbit in the kuiper belt